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Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

New
Technology / Case number: #20292JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / David Dellal / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Self-Actuating Needle/Biopsy Punch

New
Technology / Case number: #19808J
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Self-Righting Systems for Tissue Wall Localization

New
Technology / Case number: #19012JQ
Giovanni Traverso / Taylor Bensel / Daniel Minahan / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Wearable Bio-adhesive Metal Detector Array (BioMDA) for Spinal Implants

New
Technology / Case number: #26075J
Giovanni Traverso / Kewang Nan / Ganesh Shankar / Jian Li / Xinge Yu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Fluidic-Based Cell Capture and Adhesion Measurement Concept

New
Technology / Case number: #25888
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Kripa K Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Flexible Phase-Transitioning Needles for Shear Stress Reduction

New
Technology / Case number: #24651J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Spring-Loaded Double Pentograph (SLDP) Mechanism for Human Balancing and Weight Support

Technology / Case number: #25811
Ravi Tejwani / Harry Asada
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Patient-Specific Benchtop Beating Heart Simulator for Recreating Left Atrial Biomechanics and Hemodynamics for LAA Closure and HFpEF Intervention Testing

Technology / Case number: #25761
Ellen Roche / Keegan Mendez / Manisha Singh
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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Methods for Improving Statistical Power in Genetic Discovery by Incorporating Quality Control Flags

Technology / Case number: #25839P
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Shengnan Huang / Angela Belcher
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / TaeHyun Kim / Leyla Akay / Matheus Victor / Masayuki Nakano
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Single Fibre Computer Enables Textile Networks and Distributed Inference

Technology / Case number: #26084
Zi Jie Gabriel Loke / Henry Cheung / Nikhil Gupta / Syamantak Payra / Yoel Fink
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
License

Method to Release Alcohol Reporters for Profiling Disease Characteristics in Breath

Technology / Case number: #25202H
Melodi Anahtar / Shih-Ting (Christine) Wang / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Oxygenating Reservoir for Culture Media in Microphysiological Systems

Technology / Case number: #25858
Linda Griffith / Priyatanu Roy / Sydney Kim / Matthew Johnson / David L Trumper
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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