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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Deepak Dugar / Brian Pereira / Marjan De Mey / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Scott Floyd / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Generation of Specialized, High-Value Cells and Tissues from Human Induced Pluripotent Stem Cells by Recapitulating Early Embryogenesis Using Gata Factor-Induced Endoderm

Technology, Tangible Property / Case number: #16205
Ron Weiss / Patrick Guye / Mohammad Reza Ebrahimkhani
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Albert Swiston / Michael F Rubner / Robert Cohen / Darrell J Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Steven Africk / Clark Colton
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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A Synthetic Nanotube Antibody for Selective Molecular Recognition

Technology / Case number: #14090
Michael S. Strano / Jong Ho Kim / Paul Barone / Daniel Heller / Jingqing Zhang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Anti-Sigmas for Programmable Transcriptional Regulation

Technology / Case number: #15523J
Christopher Voigt / Virgil Rhodius / Carol Gross
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Covalently Functionalized Hydrogels on Oxygen Permeable Membranes for Stable, Scalable, and Xeno Free Growth of Undifferentiated Human Embryonic Stem Cells

Technology / Case number: #16162
Anna Coclite / Amanda Diienno / Karen Gleason / Clark Colton
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extra Cellular Matrix Proteins and Cancer

Technology / Case number: #15501JHR
Steven Carr / Richard Hynes / Alexandra Naba / Karl Clauser / Kenneth Tanabe
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cytosolically-Active Peroxidases as Reporters for Electron Microscopy

Technology / Case number: #15128
Jeffrey Martell / Alice Ting
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates

Technology / Case number: #12899
Jeffrey Michael Karp / Seungpyo Hong / Rohit N Karnik / Ying Mei / Suman Bose / Robert Langer / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Novel Method to Treat Myocardial Infarction and Other Tissue Damage Using Apolipoprotein D (apoD)

Technology / Case number: #15466
Kosuke Tsukamoto / Monty Krieger
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Nicolas Boyer / Justin Kim / Paul Hergenrother / Karen Morrison
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Stephen Goldfless / Jacquin Niles / Michael Marletta
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Kannan Tharakaraman / Vidya Subramanian / Devin Quinlan / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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  • Women's Health
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Method to Pattern Cells (Crude Blood) on a (Planar) Surface

Technology / Case number: #15262
Shivang Dave / German Serrano
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Improved Treatment for Organ Regeneration and Blocking Scar Formation

Technology / Case number: #25302
Ioannis Yannas
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Weida Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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