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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Louis Papa / Christopher Moore / Chet Berman / Samuel Hendel
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Compositions and Methods to Increase Muscular Strength Without Exercise

Technology / Case number: #19768
Roger Kamm / Vivek Sivathanu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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MEMS Ionizers for Compact Neutron Sources

Technology / Case number: #17549
Stephen Guerrera / Akintunde Ibitayo Akinwande
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Sustainable Future, Advanced Materials
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Delivery of Preassembled Double-Stranded Short Interference RNA-Argonaute Protein Complexes for Enhanced RNAi-Based Therapeutics

Technology / Case number: #19340
Jiahe Li / Yanpu He / Wade Wang / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mo Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Intracellular Calcium Sensors for MRI

Technology / Case number: #20143
Ali Barandov / Benjamin Bartelle / Alan Pradip Jasanoff
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Radiation Sources from the Interaction of Electron Beams with Surface Plasmon Systems

Technology / Case number: #17674
Ognjen Ilic / Yichen Shen / Liang Jie Wong / Ido Efraim Kaminer / John D Joannopoulos / Marin Soljacic
Technology Areas: Biotechnology / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Streptococcus Canis Cas9 for Tunable Genome Engineering and Regulation

Technology / Case number: #19757XTE
Noah Jakimo / Pranam Chatterjee / Joseph Jacobson
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers, Sustainable Future
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Splicing-Dependent Transcriptional Gene Silencing or Activation

Technology / Case number: #20890
Ana Fiszbein / Christopher B Burge
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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