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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Daniel Anderson / Lei Miao / Yuxuan Huang / Linxian Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit N Karnik / Chi Cheng / Chun Man Chow / Aaron Persad
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Selective Valorization of Biomass Sugars

Technology / Case number: #21846
Alison Wendlandt / Hayden Carder / Yong Wang
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Daniel Anderson / Kaelan Reed / Akash Gupta / Arnab Rudra
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Stable and Efficient Cell Surface Coupling of Nanoparticles

Technology / Case number: #17836HQ
Darrell J Irvine / Li Tang / Yiran Zheng
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Catheter for Intracardiac 3D Bioprinting

Technology / Case number: #22338J
Brett E Bouma / Markus Horvath / Sophie Wang / Milen Shishkov / Victor Damptey / Connor Verheyen / Keegan Mendez / Ellen Roche / Sebastien Uzel / Jennifer Lewis
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Targeted Layered Lipid Nanoparticles for in Vivo Extrahepatic Gene Delivery

Technology / Case number: #24751
Paula Hammond / Tamara Dacoba / Namita Nabar
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Drug Delivery Based on Bistable Membrane

Technology / Case number: #17624
Michael Cima
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Potent Agelastatin Derivatives as Modulators for Cancer Invasion and Metastasis

Technology / Case number: #19505J
Mo Movassaghi / Kun Xu / Alyssa Antropow / Rachel Buchsbaum
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mo Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Loren Walensky / Greg Bird / Raheleh Rezaei Araghi
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah A. Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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RNA-Based Regulatory Technologies for Improved miRNA Sensors

Technology / Case number: #19686
Ron Weiss / Jin Huh / Kevin Lebo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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An Oxaliplatin Crosslinker for the Formation of Drug Delivery Nanoparticles

Technology / Case number: #17532
Jeremiah A. Johnson / Jonathan Barnes / Longyan Liao
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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  • Women's Health
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Fine-Tuning pKa's of Nucleoside Analogs to Increase Mutagenicity; a Strategy to Develop More Potent Lethal Mutagen with Anti-Viral or Anticancer Properties

Technology / Case number: #17657
John M Essigmann / Sam Peng / Vipender Singh / Bogdan I Fedeles / Andrei Tokmakoff
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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