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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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DeepBAR: A Fast and Exact Method for Binding Free Energy Computation

Software / Case number: #23058
Bin Zhang / Xinqiang Ding
Technology Areas: Computer Science / Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Super-MIEC Anodes for High-Rate Lithium-Ion Batteries

Technology / Case number: #23400
Ju Li / Shitong Wang / Yanhao Dong
Technology Areas: Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Composite Multi-Material Electromechanical Energy Storage Component for Power Conversion

Technology / Case number: #23574
Jessica Boles / Joseph Bonavia / David Perreault / Jeffrey Lang
Technology Areas: Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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P3MT/Horizontally-Aligned CNT Nanocomposite for Supercapcitor with High Areal Capacitance

Technology / Case number: #21425J
Brian Wardle / Estelle Cohen / Yue Zhou / Xiaoxue Wang / Yosef (Yosi) Stein / Karen Gleason
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Aluminum-Chalcogen Batteries using Molten Salt Electrolytes

Technology / Case number: #21170
Quanquan Pang / Jiashen Meng / Ji Zhao / Donald Sadoway
Technology Areas: Energy & Distribution
Impact Areas: Advanced Materials
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Gene Delivery Carrier

Technology / Case number: #19091J
Umberto Palmiero / James Kaczmarek / Davide Moscatelli / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Advanced Materials
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Owen Fenton / Robert Langer / Jason Andresen / Marion Paolini
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Small Molecule Modulators of the Androgen Receptor

Technology / Case number: #19771
Angela Koehler / Nicholas Struntz / David Freeman / Shelby Doyle / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Max Binders Modulators of Myc-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #18257
Angela Koehler / Eric Stefan / Francisco Caballero Gonzalez / Dylan Neel / Helen Evans / Nicholas Struntz / Andrew Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Linxian Li / Yuxuan Huang / Lei Miao / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Luke Rhym / Bowen Li / Akiva Gordon / Manan manan / Jacob Witten / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A New Class of High Energy Li Primary Battery Cathodes Utilizing the Defluorination of Pentafluorosulfanyl Group

Technology / Case number: #24100
Betar Gallant / Haining Gao
Technology Areas: Energy & Distribution
Impact Areas: Advanced Materials
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit Karnik / Aaron Persad / Chun Man Chow / Chi Cheng
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Selective Valorization of Biomass Sugars

Technology / Case number: #21846
Alison Wendlandt / Yong Wang / Hayden Carder
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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