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Ultra-Thin Conformal Coating Device for Cell Therapy

Technology / Case number: #26281J
Giovanni Traverso / Henry Trainor / Boram Kim / Jong Seung Lee / Nabil Shalabi / Matt Murphy / Troy Ziliang Kang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Shuguang Zhang / Liselotte Kaiser / Joanke (Johanna) Bikker Graveland / Brian Cook / Andreas Mershin / Manu Prakash / David Kong / Yael Maguire
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Reversible and Ratiometric Sensing using Nanocrystals

Technology / Case number: #11693
Moungi G Bawendi / Rebecca Somers / Preston Snee / Daniel Nocera
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Giovanni Traverso / Taksim Ahmed / Hao Song / Xisha Huang / Simon Qu / Deepak Subramanian / Jonathan Woo / Alvin Chan / Joshua Bernstock / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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One-Step Protein Analysis Using Slanted Nanofilter Array

Technology / Case number: #17391
Jongyoon Han / Sung Ko
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Fluorescent Metal-Based Nitric Oxide Sensor for Live Cells

Technology / Case number: #11806
Stephen J Lippard / Mi Hee Lim
Technology Areas: Chemicals & Materials / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Machine-Learning Optimized Proteins and Enzymes

Technology / Case number: #26015J
Omar Abudayyeh / Zhaoqing Yan / Matteo Di Bernardo / Kaiyi Jiang / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Christopher Fell / Matthew Yarnall / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Hydrogel Carriers for Monoclonal Antibody Crystals

Technology / Case number: #21065J
Patrick Doyle / Amir Erfani Khaneghahi / Chakravarthy Narasimhan / Paul Reichert / Jeremy Schieferstein
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Darrell J Irvine / Anna Romanov / Grant Knappe / Mark Bathe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Daniel Anderson / Idris Raji / Jacob Witten / Allen Jiang / Luke Rhym
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Daniel Anderson / Idris Raji / Akiva Gordon / Bowen Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / So-Yoon Yang / Jason Li
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Robert Langer / Shady Farah / Joshua Doloff / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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