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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Rajesh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Kannan Tharakaraman / Eng Ooi / Kuan Chan / Satoru Watanabe / Subhash Vasudevan / Ram Sasisekharan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Relative Damping of Parallel Antennas for Sensing and Tuning

Technology / Case number: #24261
Alexander Peraire-Bueno / Anastasios Hart
Technology Areas: Agriculture & Food / Chemicals & Materials / Communication Systems / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Ultrathin, Conductive and Fouling-Resistant Zwitterionic Polymer Films

Technology / Case number: #19732
Minghui Wang / Peter Kovacik / Karen Gleason
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Healthy Living, Advanced Materials
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Cost-Optimal Electrodialysis Stack Design for Household Desalination

Technology / Case number: #19571
Amos Winter / Natasha Wright / Sahil Shah
Technology Areas: Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Task Specific Ionic Liquid-Impregnated Polymeric Surface Coatings for Antibacterial, Antifouling and Metal Scavenging Activity

Technology / Case number: #19124
Trevor Hatton / Paul Brown / Sahag Voskian / Cesar De la Fuente Nunez / Ryan Shaw
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Environmental Engineering
Impact Areas: Healthy Living, Advanced Materials
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Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Rohit Karnik / Emily Hanhauser / Michael Bono / Chintan Vaishnav / Sydney Beasley / Anastasios Hart
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
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Time-variant Photovoltaic Electrodialysis Systems for Community-Scale, Brackish Groundwater Desalination

Technology / Case number: #21471
Amos Winter / Kameron Conforti / Ian Marius Peters / Anne-Claire Le Henaff / Wei He / Jeffrey Costello / Simone Gelmini / Grace Connors
Technology Areas: Computer Science / Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future
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A New Approach to Cooling and Refrigeration with Zero Global Warming Potential

Technology / Case number: #23078
Asegun Henry / Mehdi Pishahang / Andrew Rohskopf / Qingzi Zhu
Technology Areas: Agriculture & Food / Chemicals & Materials / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future, Advanced Materials
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Compact Fluid Control System, Components, and End-caps for Home-Scale Electrodialysis

Technology / Case number: #24933
Amos Winter / Soraya Honarparvar / Jonathan Bessette / Zachary Sternberg / Sahas Gembali / Marie Floryan / Quinn Bowers / Akshita Goyal
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Plant Nanobionics for Enhanced Phytoremediation

Technology / Case number: #25194
Michael Strano / Cody Ritt
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Healthy Living
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Simplified Architecture for Desalination

Technology / Case number: #22537
Amos Winter / Sahil Shah / Hannah Varner / Soraya Honarparvar
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Immunostimulatory Nanoparticle Adjuvants

Technology / Case number: #20798HJ
Murillo Silva / Yu Kato / Shane Crotty / Darrell Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Chensu Wang / Darrell Irvine / Karl Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Intra-Tumoral Injection of Cytotoxic Chemotherapy-Treated Tumor Cells in Combination with Systemic Immune Checkpoint Blockade for Cancer Treatment

Technology / Case number: #21498H
Ganapathy Sriram / Lauren Milling / Darrell Irvine / Michael Yaffe
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Ron Weiss / Yingzhong Li / Jan Lonzaric / Parisa Yousefpour / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
John Love / Neil Dalvie / Sergio Rodriguez
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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