Flexible Piezoelectric Devices for Gastrointestinal Motility Sensing

This invention introduces an ingestible, flexible piezoelectric device designed to sense mechanical deformation within the gastric cavity, addressing risks associated with non-flexible gastrointestinal transiting systems. Demonstrated in in vitro and ex vivo simulated gastric models, the flexible sensor unfolds naturally and adheres to the gastrointestinal mucosa after being delivered in a dissolvable capsule. With the capacity to monitor physiological states, ingestion, and gastrointestinal motility for up to two days or more, the device offers a safe and efficient solution for diagnosing and treating motility disorders, and for monitoring ingestion in bariatric applications.