Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA
Invention type: Technology
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Case number: #24662
Provided herein are zwitterionic polymer (ZIP)-lipids and pharmaceutically-acceptable salts thereof; lipid nanoparticles (LNPs) comprising such ZIP-lipids; formulations comprising ZIP-lipid containing LNPs; methods of delivering ZIP-lipid containing LNPs, or formulations thereof, to a subject; and methods of treating a disease, disorder or condition comprising administering ZIP-lipid containing LNPs, or formulations thereof, to a subject.
Researchers
Robert Langer
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Sushil Lathwal
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Allen Jiang
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Daniel Anderson
Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
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zwitterionic polymer functionalized lipid nanoparticles for delivery of nucleic acids
United States of America | Pending
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