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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Planetary Centrifugal Deagglomeration by Transient Molten Salts for the Synthesis or Recycling of Single-Crystalline Battery Cathodes

Technology / Case number: #24878J
Ju Li / Yanhao Dong / Moonsu Yoon / Jaephil Cho
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Software Suite for Data-Driven Synthesis Planning- v0.2.0

Software / Case number: #21008
Regina Barzilay / Connor Coley / Wengong Jin / Pieter Patrick Plehiers / Hanyu Gao / Michael Fortunato / Klavs Jensen / William Green
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21604
Michael Short / Bilge Yildiz / Max Carlson / Cigdem Toparli / Minh Dinh
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Hydrogen Resistance Coatings via Hydrogen Diffusivity Minimization Based on Computationally Engineering Intrinsic and Extrinsic Defect Structure

Technology / Case number: #21800
Bilge Yildiz / Cigdem Toparli / Minh Dinh
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Gradient-Morph LiCoO2 Single Crystals with Stabilized Energy-Density above 3400 Wh/L in Full-Cells

Technology / Case number: #22063
Ju Li / Zhi Zhu / Yimeng Huang
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Surface Se-substituted Li1+x[Co,Ni,Mn,Al]1-x[O2-Se] cathode with Ultrastable High-Voltage Cycling in Pouch Full-Cells

Technology / Case number: #22686
Ju Li / Zhi Zhu
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future, Connected World
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Methane Upgrade to Ethane and Ethylene within Ceramic Membrane Reactors

Technology / Case number: #22915
Ahmed Ghoniem / Bilge Yildiz / Georgios Dimitrakopoulos
Technology Areas: Chemicals & Materials
Impact Areas: Connected World
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Method and Apparatus for In-Situ Production of Ammonia or Ammonium Salts from N2 via Subsurface Ge

Technology / Case number: #25171
Ju Li / Iwnetim Abate
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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This is the Instructional Materials which Accompany the Hands-on Set of Educational Building Blocks to Model the Process of Assembly of Proteins from Amino Acids

Case number: #20437C
John Vandiver
Technology Areas: Communication Systems / Therapeutics
Impact Areas: Healthy Living, Connected World
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Instructional Materials in Support of: Set of Educational Building Blocks to Model Nucleic Acid Structures

Case number: #20438C
John Vandiver
Technology Areas: Communication Systems / Therapeutics
Impact Areas: Healthy Living, Connected World
License

Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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