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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Planetary Centrifugal Deagglomeration by Transient Molten Salts for the Synthesis or Recycling of Single-Crystalline Battery Cathodes

Technology / Case number: #24878J
Ju Li / Yanhao Dong / Moonsu Yoon / Jaephil Cho
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Software to Compute the Elastic Response of Thin Plates and Shells (Monolayers and Bilayers) to Growth

Software / Case number: #20823
Willem van Rees
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Sustainable Future
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Vector Representations of Protein Sequences Learned from Structure (Software)

Software / Case number: #20851
Tristan Bepler
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Software Suite for Data-Driven Synthesis Planning- v0.2.0

Software / Case number: #21008
Regina Barzilay / Connor Coley / Wengong Jin / Pieter Patrick Plehiers / Hanyu Gao / Michael Fortunato / Klavs Jensen / William Green
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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A Software Platform for Transcriptomic Analysis

Software / Case number: #21368
Paul Boutz / Arjun Bhutkar / Arundeep Singh
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21604
Michael Short / Bilge Yildiz / Max Carlson / Cigdem Toparli / Minh Dinh
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Hydrogen Resistance Coatings via Hydrogen Diffusivity Minimization Based on Computationally Engineering Intrinsic and Extrinsic Defect Structure

Technology / Case number: #21800
Bilge Yildiz / Cigdem Toparli / Minh Dinh
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Gradient-Morph LiCoO2 Single Crystals with Stabilized Energy-Density above 3400 Wh/L in Full-Cells

Technology / Case number: #22063
Ju Li / Zhi Zhu / Yimeng Huang
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Surface Se-substituted Li1+x[Co,Ni,Mn,Al]1-x[O2-Se] cathode with Ultrastable High-Voltage Cycling in Pouch Full-Cells

Technology / Case number: #22686
Ju Li / Zhi Zhu
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future, Connected World
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Methane Upgrade to Ethane and Ethylene within Ceramic Membrane Reactors

Technology / Case number: #22915
Ahmed Ghoniem / Bilge Yildiz / Georgios Dimitrakopoulos
Technology Areas: Chemicals & Materials
Impact Areas: Connected World
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Method and Apparatus for In-Situ Production of Ammonia or Ammonium Salts from N2 via Subsurface Ge

Technology / Case number: #25171
Ju Li / Iwnetim Abate
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Machine Learning Models for Data-Driven Bioprocess Development

Software / Case number: #23675
Connor Coley / Aparajita Dasgupta
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living, Connected World
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Using CRISPR/Cas9 to Encode Cellular History

Technology / Case number: #18025R
Alexander Shalek / Alethe Gaillard de Saint Germain
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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