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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Carlo Giovanni Traverso / Hen Wei Huang / James Byrne
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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P3MT/Horizontally-Aligned CNT Nanocomposite for Supercapcitor with High Areal Capacitance

Technology / Case number: #21425J
Brian Wardle / Estelle Cohen / Yue Zhou / Xiaoxue Wang / Yosef (Yosi) Stein / Karen Gleason
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Wireless Interlaminar Sensor (WINS): CNT Delamination Sensor with Environmental Compensation

Technology / Case number: #23855J
Brian Wardle / Luiz Henrique Acauan / Yosef (Yosi) Stein / Haozhe Wang / Haim Primo
Technology Areas: Chemicals & Materials / Communication Systems / Sensing & Imaging
Impact Areas: Advanced Materials
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Pupil Engineering Method to Enhance the Signal of the Real-time non-invasive Particle Size Distribution Probe in Powders and During Mixing, Drying, Blending, and Milling Processes

Technology / Case number: #24521
Allan Myerson / Richard Braatz / Qihang Zhang / Zhen Guo / Ajinkya Vikram Pandit / George Barbastathis
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
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Methods for Producing High-Level Squalene in Yarrowia Lipolytica

Technology / Case number: #24579
Yongshuo Ma / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Temperature Miniature Ultrasonic Probes

Technology / Case number: #24612
Hoagy O'Ghaffari / Matej Pec
Technology Areas: Sensing & Imaging
Impact Areas: Advanced Materials
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Device and Method for Imaging Shortwave Infrared Autofluorescence

Technology / Case number: #18527J
Oliver Bruns / Jessica Carr / Klaus Van Leyen / Yi Zheng / Marianne Aellen / Moungi Bawendi
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Spray-Coating Method with Particle Alignment Control

Technology / Case number: #18817J
Dayong Chen / Roberta Polak / Kenan Song / Khalid Askar / Michael Rubner / Robert Cohen
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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In-Pipe Leak Detection System

Technology, Tangible Property / Case number: #19034JC
Rached Ben-Mansour / You Wu / Kristina Kim / Michael Henry / Kamal Youcef-Toumi
Technology Areas: Agriculture & Food / Environmental Engineering / Sensing & Imaging
Impact Areas: Sustainable Future
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Carlo Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Peggy Hsu / David Sykes / Frances Diehl
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Photosensitized-Photoactive Materials and Methods for Making and Using the Same

Technology / Case number: #17987J
Mohammad Gondal / Gibum Kwon / Gareth McKinley / Kripa Varanasi
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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