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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley Pentelute / Andrei Ioan Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Mammalian Synthetic Biology Approaches for the Precise Control of mAb N-Glycosylation (Pfizer-MIT PTM Track 2 Interim Joint Summary Document)

Technology / Case number: #19972J
Timothy Lu / Ron Weiss / Nevin Summers / Wen Tseng / Leonid Gaydukov / Michelle Chang / Giyoung Jung / Richard Cornell / Jeffrey Marshall / John Scarcelli / Bruno Figueroa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Enhanced Endogenous Recombination for Gene Therapy and Genetic Engineering

Technology / Case number: #20008M
Guoping Feng / Jonathan Wilde / Tomomi Aida / Martin Wienisch / Qiangge Zhang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Systems and Assays for Identifying PU.1 Inhibitors

Technology / Case number: #21734P
Li-Huei Tsai / William Ralvenius / Alison Mungenast
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Ron Weiss / Yingzhong Li / Jan Lonzaric / Parisa Yousefpour / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Centrifugal Microfluidic Platforms for Cell Pairing and Fusion

Technology / Case number: #22275J
MohammadMahdi Aeinhvand / Sergio Martínez-Chapa / Sergio Martinez-Chap / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Activatable Antimicrobial Peptides and Uses Thereof

Technology / Case number: #24024H
Chayanon Ngambenjawong / Sangeeta Bhatia
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Universal Redirection of Chimeric Antigen Receptor T Cells Against Solid Tumors via Tumor Cell Membrane-Inserting CAR Ligands

Technology / Case number: #24270H
Angela Zhang / Laura Chen / Alexander Hostetler / Darrell Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
John Love / Neil Dalvie / Sergio Rodriguez / Kristen Rodrigues / Darrell Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Autocatalytic Base Editing for RNA-Responsive Translational Control

Technology / Case number: #24552YJ
James Collins / Raphael Gayet / Katherine Ilia / Shiva Razavi / Nathaniel Tippens / Kehan Zhang / Xiaoyu Chen / Jonathan Chen / Makoto Lalwani
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Temporally Multiplexed Imaging Technology

Technology / Case number: #24554MH
Edward Boyden / Yong Qian
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Molecular Memory Retrieval by Position-based Addressing

Technology / Case number: #21829
Tyson Shepherd
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Connected World
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Protein-Surfactant-Monomer/Polymer Blends for Protein-Based Elastomers

Technology / Case number: #19861
Bradley Olsen / Wui Yarn Chan
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Microbial Production of Renewable Glycolate

Technology / Case number: #18161
Brian Pereira / Zheng-Jun Li / Gregory Stephanopoulos
Technology Areas: Biotechnology / Environmental Engineering
Impact Areas: Sustainable Future
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Strain and Bioprocess Engineering for High Lipid Production

Technology / Case number: #18140
Kangjian Qiao / Peng Xu / Gregory Stephanopoulos
Technology Areas: Biotechnology / Environmental Engineering
Impact Areas: Sustainable Future
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 75 results

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