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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Enhancement of Lignocellulosic Fermentation in S. Cerevisiae by Combined Genetic Modulations and Media Supplementation

Technology / Case number: #21982WJ
Felix Lam / Gregory Stephanopoulos / Gerald Fink
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Methods for Producing High-Level Squalene in Yarrowia Lipolytica

Technology / Case number: #24579
Yongshuo Ma / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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An App for Quantifying Band Intensities from Diagnostic Lateral Flow Strips

Software / Case number: #22475
James Collins / Miguel Alcantar / Michael Kaminski / Jacqueline Valeri
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Engineered Protein Treatments for Hair Repair and Long-Lasting Color Retention

Technology / Case number: #19806
Bradley Olsen / Sieun Kim
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Organelle-Selective Gene Delivery and Expression in the Chloroplast in planta using Chitosan-Complexed Single-Walled Carbon Nanotube Carriers

Technology / Case number: #20537
Michael Strano / Seonyeong Kwak / Tedrick Salim Lew
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Sustainable Future
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Next Generation Light-emitting Plant-longer Duration and Brighter

Technology / Case number: #20563
Michael Strano / Seonyeong Kwak / Pavlo Gordiichuk
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Uncharted Frontiers
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Paper-Immobilized Optical Nanosensors

Technology / Case number: #20969
Michael Strano / Xun Gong / Daniel Salem
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Advanced Materials
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Charged Hydrogels for Concentrating Proteins

Technology / Case number: #24139
Baptiste Blanc / Fabian Dickhardt / Kripa Varanasi
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Thermal Imaging-based State Estimation of a Stefan Problem with Application to Cell Thawing

Technology / Case number: #24616
Allan Myerson / Richard Braatz / Qihang Zhang / Moo Sun Hong / Ajinkya Vikram Pandit / Prakitr Srisuma / George Barbastathis
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Machine Learning for the Discovery of Nanomaterial-based Molecular Recognition

Technology / Case number: #23691
Michael Strano / Retsef Levi / Xun Gong / Nicholas Renegar
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Additively Manufactured Mesh Materials

Technology / Case number: #20719
Sebastian Pattinson / Meghan Huber / Jongwoo Lee / Ricardo Esteban Roberts Ugrinovic / Anastasios Hart
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Christopher Voigt / Uyanga Tsedev / Tae-Gon Cha / Angela Belcher
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Characterization and Utilization of a Subgenomic Promoter Mutant Library for Tuning Expression of Multiple Transgenes from Alphavirus Replicons

Technology / Case number: #21309
Ron Weiss / Jin Huh
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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MicroRNA-based Logic Gates that Do Not Use Exogenous Proteins

Technology / Case number: #21334
Ron Weiss / Giulio Alighieri
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Gene Therapy in Mammalian Cells by the use of the Strand Displacement Reaction

Technology / Case number: #21486
Ron Weiss / Giulio Alighieri
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Endogenous Gene Sensing and Actuation by Placement of Non-Coding RNA after Transcriptional Termination Signals

Technology / Case number: #21520
James Collins / Ron Weiss / Jeremy Gam / Elvira Vitu / Casper Enghuus
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Endoribonuclease-based Incoherent Feedforward Loop for Accurate Control of Gene Expression Levels in Mammalian Cells

Technology / Case number: #21843
Ron Weiss / Ross Jones / Breanna DiAndreth / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cheaper, Environmentally Friendly, and Sustainable Biofuel Production through Yeast System

Technology / Case number: #21974
Shalmalee Pandit / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Sustainable Future
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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