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Oral Pill Water-Tight Payload Chamber Design with Triggerable Release

Technology / Case number: #25209J
Carlo Giovanni Traverso / Miguel Jimenez / James McRae / Emily Kolaya
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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A Microphysiological Model of the Brain Including Blood-brain Barrier, Neural Tissue and Meningeal Lymphatics

Technology / Case number: #24291
Roger Kamm
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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NetCast: Low-Power Edge Computing with Optical Neural Networks via WDM Weight Broadcasting

Technology / Case number: #22737J
Dirk Englund / Ryan Hamerly
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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A Novel Bio-Inspired Actuator Design

Technology / Case number: #24990
Daniela Rus / Chao Liu / Andrea Moncada / Hania Matusik / Deniz Erus
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Connected World
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Mobile Physical Telemedicine

Technology / Case number: #24924
Johannes Lachner / Federico Tessari / Neville Hogan
Technology Areas: Biotechnology / Communication Systems / Computer Science / Industrial Engineering & Automation
Impact Areas: Healthy Living, Uncharted Frontiers, Connected World
License

A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Carlo Giovanni Traverso / Hen Wei Huang / Siheng You / Erin Raftery / Canchen Li
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Implantable Devices for the Ejected Delivery of Stable, Dry Powder Forms of Drugs

Technology / Case number: #24835J
Robert Langer / Arnab Rudra / Siddharth Krishnan / Nima Khatib / Laura OKeeffe / Daniel Anderson
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Millineedle Systems for Esophageal Drug Delivery

Technology / Case number: #20939J
Carlo Giovanni Traverso / Ester Caffarel Salvador / Robert Langer / Sahab Babaee / Simo Pajovic
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Luminal Unfolding Micro-Injectors for Drug Delivery

Technology / Case number: #20106JQ
Carlo Giovanni Traverso / Daniel Minahan / Alex Abramson / Ester Caffarel Salvador / Vance Soares / Robert Langer
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
License

Quick Release Capsules for Small Intestine Delivery

Technology / Case number: #20105J
Carlo Giovanni Traverso / Daniel Minahan / Alex Abramson / Niclas Roxhed / Ester Caffarel Salvador / David Dellal / Vance Soares / Robert Langer / Christoph Winfried Johannes Steiger / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Technology / Case number: #23258J
Polina Anikeeva / Carlo Giovanni Traverso / Shriya Srinivasan / Robert Langer / Marc-Joseph Antonini
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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