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Drinkable, Tough Hydrogels for Gastrointestinal Applications

New
Technology / Case number: #24642JQ
Carlo Giovanni Traverso / Robert Langer / Gary Liu / Matthew Pickett
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

New
Technology / Case number: #24942
Omar Abudayyeh / Jonathan Gootenberg / Justin Lim / Kaiyi Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

New
Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
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Chemical Formulations to Enhance Ultrasound-Mediated Gastrointestinal Delivery

Technology / Case number: #19050JQ
Carlo Giovanni Traverso / Carl Schoellhammer / Thomas Von Erlach / Taylor Bensel / Daniel Minahan / Robert Langer
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Interbilayer-Crosslinked Multilamellar Vesicles for Vaccine and Drug Delivery Applications

Technology / Case number: #14194H
Jae Hyun (James) Moon / Darrell Irvine
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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2-Aminoindole-Class Antimalarials

Technology / Case number: #14097BJ
Ralph Mazitschek / Sameer Urgaonkar / Cassandra Celatka / Dyann Wirth / Roger Wiegand / Mary Lynn Baniecki / Joseph Cortese / Edmund Sybertz / Renato Skerlj / Yibin Xiang / Elyse Bourque / Jon Clardy
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Hydrophobic Polycationic Coatings That Inhibit Biofilm Formation on Orthopedic Implants and Support Healing During Infection in Sheep

Technology / Case number: #15031J
Bryan Hsu / Thomas Schaer / Suzanne Stewart / Alexander Klibanov
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Manu Prakash / Andreas Mershin / Brian Cook / Joanke (Johanna) Bikker Graveland / Liselotte Kaiser / Shuguang Zhang / Yael Maguire / David Kong
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
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Fabrication of Electrostatically Mediated and Self-Assembled Monolayer of Macromolecules on Mobility-Enhancing Polyelectrolyte Multilayer

Technology / Case number: #11837
Piljin Yoo / Soo-Kwan Lee / Paula Hammond / Juhyun Park / Angela Belcher / Ki Tae Nam / Jifa Qi
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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"Comet Chip": Electrophoresis of Arrayed Cells for Analysis of DNA Damage and Repair

Technology / Case number: #13158
Bevin Engelward / David Wood / David Weingeist / Sangeeta Bhatia
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Utilization of Cyclodextrins for Drug Delivery from Degradable Layer-By-Layer Films

Technology / Case number: #12978
Renee Smith / Paula Hammond
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Reversible and Ratiometric Sensing using Nanocrystals

Technology / Case number: #11693
Preston Snee / Rebecca Somers / Moungi Bawendi / Daniel Nocera
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Therapeutics
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An Approach for Enriching the Production of DNA Cargo Loaded AAV5 Capsids in Cells

Technology / Case number: #25585
Paul Barone / Richard Braatz / Anthony Sinskey / Stacy Springs / Rui Wen Ou / Jacqueline Wolfrum / Prasanna Srinivasan / John Joseph
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Arturo Vegas / Yair Levi / Yunlong Zhang / Benjamin Tang / Hung-Chieh (Danny) Chou / Kun Xue / Matthew Webber / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Carlo Giovanni Traverso / Ameya Kirtane / Joshua Bernstock / Alvin Chan / Jonathan Chek Kwon Woo / Deepak Subramanian / Simon Qu / Xisha Huang / Hao Song / Taksim Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
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Mucin-Inspired Glycopolypeptides for Managing Microbial Infections

Technology / Case number: #26189J
Katharina Ribbeck / Kelsey Wheeler / Michaela Gold / Jessica Kramer
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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A Computational Method for Identifying the Biophysical Interactions that Determine Human T Cell Specificity from Structural Data and Primary Amino Acid Sequences

Technology / Case number: #26026J
Xingcheng Lin / Herbert Levine / José Onuchic / Ailun Wang / Jason George
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Zhen Gu / Alex Aimetti / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

A Novel Multiplexed Inertial Focusing Microfiltration System for Intra-Operative Blood Salvage Autotransfusion

Technology / Case number: #17212DJE
Chwee-Teck Lim / Guofeng Guan / Lidan Wu / Majid Ebrahimi Warkiani / Kah Ping Andy Tay / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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