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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods And Compositions For High-Throughput Compressed Screening For Therapeutics

Technology / Case number: #21936RH
Alexander Shalek / Benjamin Mead / Conner Kummerlowe / No Inventor
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Tri-Functional Hydrophilic Self-Crosslinked Dimethylacrylamide Polymer

Technology / Case number: #18698TEM
Edward Boyden / Linyi Gao / Ruixuan Gao / Nikita Obidin
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Motion Sensing Wi-Fi Sensor Networks for Continuous 3D Modeling and Prediction of Facility Responses to Disturbances

Technology / Case number: #18174J
Oral Buyukozturk / Neal Wadhwa / Hossein Mobahi / Zoran Dzunic / Justin Chen / James Long / Reza Mohammadi Ghazi Mahalleh / Sergio Kapusta / Dirk Smit / William Freeman / John Fisher III / Frederic Durand (he/him/his)
Technology Areas: Communication Systems / Sensing & Imaging
Impact Areas: Connected World
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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Miniature Spectrometer Based on Mid-Field Diffraction Imaging

Technology / Case number: #18164
Amir Atabaki / Ningren Han / Erika Ye / William Herrington / Rajeev Ram
Technology Areas: Chemicals & Materials / Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
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Using Radar Imaging of Propagating Acoustic Waves to Constrain Models of Mechanical Properties in an Heterogeneous Near Surface Imaging System

Technology / Case number: #21643J
Stephen Brown / Michael Fehler / Thomas Szabo / Daniel Burns
Technology Areas: Sensing & Imaging
Impact Areas: Connected World
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Cryo-Compatible Universal Substrates for In-Situ Quantum Microscopy Imaging and Characterization

Technology / Case number: #25421
Dirk Englund / Jawaher Almutlaq / Mohamed ElKabbash
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions and Methods for Inhibiting Expression of the Signal Regulatory Protein Alpha Gene

Technology / Case number: #23695J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Gevorg Grigoryan / Justin Jenson / Vincent Xue / Jianfu Zhou
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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