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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diagnosis of Malignancy Using Developmental Relationships and Machine Learning

Technology / Case number: #23356
Salil Garg / Enrico Moiso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Carlo Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Enhancement of Lignocellulosic Fermentation in S. Cerevisiae by Combined Genetic Modulations and Media Supplementation

Technology / Case number: #21982WJ
Felix Lam / Gregory Stephanopoulos / Gerald Fink
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Devices, Methods and Systems for Recycling Combustion Ash

Technology / Case number: #22655J
Elsa Olivetti / Venkat Viswanathan / Leah Ellis / Sophie Coppieters T Wallant / Sonia Zhang / Michael Wang / Yet-Ming Chiang
Technology Areas: Environmental Engineering
Impact Areas: Sustainable Future
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Electrochemical Direct Air Capture of CO2 Using Neutral Red as Reversible Redox-Active Material

Technology / Case number: #24363
Trevor Hatton / Hyowon Seo
Technology Areas: Environmental Engineering
Impact Areas: Climate Stabilization
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Catalytic Oxidation Reactors for the Removal of Low-Level Methane in Air

Technology / Case number: #24434
Desiree Plata / Asegun Henry / Mehdi Pishahang / Qingzi Zhu / Rebecca Brenneis / Anastasios Hart
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Advanced Materials
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Direct-Drive (Batteryless) Electrodialysis Separation using Flow-Commanded Current Control

Technology / Case number: #24538
Amos Winter / Shane Pratt / Jonathan Bessette
Technology Areas: Environmental Engineering
Impact Areas: Sustainable Future
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Controller for Management of Optimal Schedules, used with Renewable-Energy Powered Irrigation Systems

Technology / Case number: #24578
Amos Winter / Georgia Van de Zande / Fiona Grant / Shane Pratt / Carolyn Sheline / Simone Gelmini
Technology Areas: Agriculture & Food / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Methods for Producing High-Level Squalene in Yarrowia Lipolytica

Technology / Case number: #24579
Yongshuo Ma / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Photoelectrochemical Capture of Acid Gases (Solar-Driven Carbon Dioxide Capture)

Technology / Case number: #24581
Trevor Hatton / Alexandra Victoria Tavasoli / Vittoria Bolongaro / Kyle Diederichsen
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Electrochemical CO2 Conversion Architecture

Technology / Case number: #24598
Simon Rufer / Kripa Varanasi
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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In-Pipe Leak Detection System

Technology, Tangible Property / Case number: #19034JC
Rached Ben-Mansour / You Wu / Kristina Kim / Michael Henry / Kamal Youcef-Toumi
Technology Areas: Agriculture & Food / Environmental Engineering / Sensing & Imaging
Impact Areas: Sustainable Future
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Peggy Hsu / David Sykes / Frances Diehl
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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