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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Gevorg Grigoryan / Justin Jenson / Vincent Xue / Jianfu Zhou
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Technology / Case number: #23258J
Polina Anikeeva / Carlo Giovanni Traverso / Shriya Srinivasan / Robert Langer / Marc-Joseph Antonini
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Glucose-Responsive Glucagon Formulations for Closed-Loop Prophylactic Treatment of Hypoglycemia

Technology / Case number: #21838J
Carlo Giovanni Traverso / Robert Langer / Jason Li / Se Jun Lee
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Wireless Interlaminar Sensor (WINS): CNT Delamination Sensor with Environmental Compensation

Technology / Case number: #23855J
Brian Wardle / Luiz Henrique Acauan / Yosef (Yosi) Stein / Haozhe Wang / Haim Primo
Technology Areas: Chemicals & Materials / Communication Systems / Sensing & Imaging
Impact Areas: Advanced Materials
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Functionalized Aramid Amphiphile Self-assembled Nanostructures as Nano-reactors in Aqueous Environment

Technology / Case number: #24369
Julia Ortony / Yukio Cho / Kiera Tai
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Pants with Embedded Harness for Daily Use

Technology / Case number: #24380
Emily Kamienski / Karen Chen / Haruhiko Asada
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Catalytic Oxidation Reactors for the Removal of Low-Level Methane in Air

Technology / Case number: #24434
Desiree Plata / Asegun Henry / Mehdi Pishahang / Qingzi Zhu / Rebecca Brenneis / Anastasios Hart
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Advanced Materials
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Hydrogen Selective Membranes

Technology / Case number: #24437
Rohit Karnik / Randall Field / Aaron Persad / Chi Cheng / Lohyun Kim
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Pupil Engineering Method to Enhance the Signal of the Real-time non-invasive Particle Size Distribution Probe in Powders and During Mixing, Drying, Blending, and Milling Processes

Technology / Case number: #24521
Allan Myerson / Richard Braatz / Qihang Zhang / Zhen Guo / Ajinkya Vikram Pandit / George Barbastathis
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
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Low-Temperature Synthesis of Two-Dimensional Materials

Technology / Case number: #24560
Jing Kong / Tomas Palacios / Jiangtao Wang / Jiadi Zhu / Ji Hoon Park
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Method of Forming Topcoat for Patterning

Technology / Case number: #18405QJ
Priya Moni / Do Han Kim / Paul Nealey / Hyo Seon Suh / Karen Gleason
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Spray-Coating Method with Particle Alignment Control

Technology / Case number: #18817J
Dayong Chen / Roberta Polak / Kenan Song / Khalid Askar / Michael Rubner / Robert Cohen
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Multiscale Porous High-Temperature Heat Exchanger

Technology / Case number: #21240J
Evelyn Wang / Lin Zhao / Bikramjit Bhatia / Arny Leroy / Kyle Wilke / Lenan Zhang / Xiangyu Li / Jeffrey Youngblood / Rodney Trice / Chad Wilson / Olivia Brandt / Rodrigo Guerra
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Metal-Halogen Batteries using Immiscible Solvents

Technology / Case number: #21901V
Andres Badel / Fei Wang / Yet-Ming Chiang
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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