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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Tri-Functional Hydrophilic Self-Crosslinked Dimethylacrylamide Polymer

Technology / Case number: #18698TEM
Edward Boyden / Linyi Gao / Ruixuan Gao / Nikita Obidin
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Device and Method for Imaging Shortwave Infrared Autofluorescence

Technology / Case number: #18527J
Oliver Bruns / Jessica Carr / Klaus Van Leyen / Yi Zheng / Marianne Aellen / Moungi Bawendi
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Carlo Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Jeffrey Karp / Xiaolei Yin / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Carlo Giovanni Traverso / Hen Wei Huang / Seungho Lee / Saurav Maji / Peter Chai / Tom Kerssemakers / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Angela Koehler / Natalie Boehnke / Joelle Straehla / Paula Hammond
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Latent-Fluoride Containing Polymers for Triggered Degradation

Technology / Case number: #23066
Jeremiah Johnson / Peyton Shieh / Christopher Brown
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Field Dependent Sensors from Redox Active Carbon Nanomaterials

Technology / Case number: #19822J
Suchol Savagatrup / Maggie He / Sibo Lin / Vera Schroeder / Xi-Xiang Zhang / Khaled Salama / Timothy Swager
Technology Areas: Chemicals & Materials / Energy & Distribution / Sensing & Imaging
Impact Areas: Healthy Living
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Selective Valorization of Biomass Sugars

Technology / Case number: #21846
Alison Wendlandt / Yong Wang / Hayden Carder
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Near and Shortwave Infrared Polymethine Dyes

Technology / Case number: #19474
Ellen Sletten / Justin Caram / Timothy Swager
Technology Areas: Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Rohit Karnik / Emily Hanhauser / Michael Bono / Chintan Vaishnav / Sydney Beasley / Anastasios Hart
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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