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Biomarkers Derived from Neurophysiological Computational Modeling

Technology / Case number: #18088L
Satrajit Ghosh / Jeffrey Palmer / Christopher Smalt / Brian Helfer / Daryush Mehta / James Williamson / Gregory Ciccarelli / Joseph Perricone / Thomas Quatieri
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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End to End Deep Neural Network for Auditory Attention Decoding

Technology / Case number: #21085LJ
Christopher Smalt / Gregory Ciccarelli / Joseph Perricone / Thomas Quatieri / Michael Brandstein / Paul Calamia / Stephanie Haro / Michael Nolan / Nima Mesgarani / James O'Sullivan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Jianghong Min / Charleston Noble
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
Edward Wack / Anna Shcherbina / Brian Helfer / Darrell Ricke / Joseph Isaacson / Adam Michaleas / Philip Fremont-Smith / James Watkins / James Harper / Martha Petrovick / Eric Schwoebel
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Automated Surface Area Assessment for Dermatologic Lesions

Technology / Case number: #19792J
Priyanka Raina / Jiarui Huang / Victor Huang / Anantha Chandrakasan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Superconducting Parametric Amplifier Neural Network

Technology / Case number: #21125L
Alexander Wynn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Methods for Learning Network Architectures of Deep Convolutional Neural Networks under Resource Constraints

Technology / Case number: #20095L
Luke Skelly / Jason Thornton / Michael Chan / Ronald Duarte / Daniel Scarafoni
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732
Fang Kong / Subra Suresh / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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RNAI-Based Method of Screening and Characterizing Drug Combinations

Technology / Case number: #19756
Michael Hemann / Justin Pritchard / Douglas Lauffenburger
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Learning-Guided Electron Microscopy

Technology / Case number: #21380J
Yaron Meirovitch / Aravinathan Samuel / Lu Mi / Jeff Lichtman / Nir Shavit
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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All-Photonic Artificial Neural Network Processor Via Non-linear Optics

Technology / Case number: #23925
Dirk Englund / Mikkel Heuck / Stefan Krastanov / Jasvith Basani
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Connected World, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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