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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Patrick Doyle / Daniel Pregibon / Ramin Haghgooie / Mehmet Toner
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Method to Improve the Image Quality of Positron Emission Tomography When Using Non-Standard Isotopes Based on Triple Coincidences

Technology / Case number: #16135
Shivang Dave / Vicente Parot / Eduardo Lage / Joaquin Herraiz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Weight Sensing

Technology / Case number: #26101
Steven Burcat / Alexander Slocum / Rohan Kadambi / Bernhardt Trout
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Manu Prakash / Andreas Mershin / Brian Cook / Joanke (Johanna) Bikker Graveland / Liselotte Kaiser / Shuguang Zhang / Yael Maguire / David Kong
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Daniel Klein-Marcuschamer / Gregory Stephanopoulos
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reverse Micelle Nanoprecipitation: A Method for Encapsulating Nucleic Acids in Biodegradable Polymers

Technology / Case number: #12561J
Aleksandar Radovic-Moreno / Liangfang Zhang / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Computer Science / Electronics & Photonics
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Disrupted in Schizophrenia 1 (DISC-1) Interacts with the Wnt Signaling Pathway and Regulates Neurogenesis

Technology / Case number: #12654HBJ
Li-Huei Tsai / Stephen Haggarty / Yingwei Mao / Jon Madison
Technology Areas: Chemicals & Materials / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kristala Prather / Kevin Solomon
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Fabrication of Electrostatically Mediated and Self-Assembled Monolayer of Macromolecules on Mobility-Enhancing Polyelectrolyte Multilayer

Technology / Case number: #11837
Piljin Yoo / Soo-Kwan Lee / Paula Hammond / Juhyun Park / Angela Belcher / Ki Tae Nam / Jifa Qi
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Utilization of Cyclodextrins for Drug Delivery from Degradable Layer-By-Layer Films

Technology / Case number: #12978
Renee Smith / Paula Hammond
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Arturo Vegas / Yair Levi / Yunlong Zhang / Benjamin Tang / Hung-Chieh (Danny) Chou / Kun Xue / Matthew Webber / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Mitchell Tai / Sagar Chakraborty / Gregory Stephanopoulos
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Carlo Giovanni Traverso / Ameya Kirtane / Joshua Bernstock / Alvin Chan / Jonathan Chek Kwon Woo / Deepak Subramanian / Simon Qu / Xisha Huang / Hao Song / Taksim Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
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A Computational Method for Identifying the Biophysical Interactions that Determine Human T Cell Specificity from Structural Data and Primary Amino Acid Sequences

Technology / Case number: #26026J
Xingcheng Lin / Herbert Levine / José Onuchic / Ailun Wang / Jason George
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Shayan Mukherjee / Daniela Tropea / Gabriel Kreiman / Mriganka Sur / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Information-Theoretic Approach for Analyzing Chromatin State Models

Technology / Case number: #17666
Manolis Kellis / Wouter Meuleman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Gizem Akcay / R. Collier
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extension of a Finite Element Framework for Calculation of DNA Nanostructure Solution Shape, Mechanical, and Optical Properties

Technology / Case number: #16421
Mark Bathe / Do-Nyun Kim / Matthew Adendorff / Keyao Pan / Lun Yang / Reza Sharifi Sedeh / Etienne Boulais / Oskar Hallatschek / Klaus-Jurgen Bathe
Technology Areas: Computer Science
Impact Areas: Healthy Living
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Normalization Correction for Inter-Detector Scatter Enhanced Positron Emission Tomography

Technology / Case number: #16136
Shivang Dave / Vicente Parot / Eduardo Lage / Joaquin Herraiz
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Machine-Learning Optimized Proteins and Enzymes

Technology / Case number: #26015J
Omar Abudayyeh / Jonathan Gootenberg / Lukas Villiger / Kaiyi Jiang / Matteo Di Bernardo / Zhaoqing Yan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Therapeutics
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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