- The RADARs can function with either endogenous cellular ADAR or exogenous ADAR.
Ability to control expression of synthetic mRNA, an important feature for mRNA therapeutics and vaccines.
Detection sensitivity on endogenous transcripts as low as 13 transcripts per million (TPM).
This technology can be expressed via DNA or synthetic mRNA.
A wide variety of payloads can be attached to the sensor system, which the inventors have demonstrated for luciferase, fluorescent proteins, and caspases.