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This technology uses ion concentration polarization (ICP) to electromechanically lyse bacteria. It can harvest the resulting intracellular biomaterials (e.g., DNA, RNA, and proteins) and metabolites (e.g., biodiesels, bioplastics, antibiotics, and antibodies). It may also be used industrially as a large-scale, continuous, power-efficient, and portable sterilization device for water disinfection, wastewater treatment, cleaning aquariums, and food/beverage sterilization.