This biological deposition detection device utilizes an electrical resonator: a sensor that is positioned on the surface of a medical device prior to implantation. The sensor has resonant frequencies that are altered by the extent and properties of deposition on the medical device surface. This device also utilizes an external hand-held measurement system: a reader capable of wirelessly determining the sensor’s resonant frequencies. The electrical permittivity of depositions such as thrombus, pannus, endothelial cells, pathogenic biofilms, and human blood are distinct due to differences in molecular composition and spatial geometry of the cells. As biological deposition builds, the sensor’s resonant frequencies change. After processing the change in resonant frequencies, the reader delivers a deposition report to the user. In conjunction with other clinical data, healthcare providers may use this information to help inform patient treatment.