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Problem Addressed

The formation of harmful biological deposition such as thrombus, pannus, and biofilm can lead to a heart attack or stroke, increase the risk of sepsis, or necessitate the replacement of implants. Identifying the formation of endothelial cells on implants is important for clinicians, because it may prevent thrombus formation. Current biological deposition detection procedures include cinefluoroscopy, transthoracic and transoesophageal echocardiography, and angiography. These methodologies only detect either functional impairment of mechanical implants or large depositions that obstruct blood flow. They fail to identify the extent and properties of deposition on implanted medical devices. There is a need for a device, such as this, that can identify and monitor the deposition of beneficial and harmful biological materials on implantable medical devices.