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Problem Addressed

Economic and environmental concerns about petrochemical usage have led to increased interest in biofuels. Alcohols with medium to long carbon chains (C5 or greater) are attractive biofuels with a high energy density, but are not naturally produced in microorganisms. Previous metabolic engineering efforts have generally produced an insufficient yield for commercial purposes, especially due to large amounts of related byproducts. As yet, no large-scale production of 4MP in particular has been achieved. The novel synthesis route described within is capable of producing 4MP with high selectivity for industrial synthesis, and can be altered to synthesize a variety of branched, medium chain alcohols.