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Problem Addressed

During a heart attack,  the obstruction of blood flow to cardiac tissue leads to cell death that reduces the ability of the heart to contract effectively.   Recent developments in regenerative tissue engineering have led to the development of cardiac patches, or cardiomyocytes seeded into a hydrogel matrix, with the aim of growing these cells into a functional implant to heal the damaged tissue.  However, cardiomyocytes neither proliferate well nor regain their function under these conditions.