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Advantages

  • Conservancy of siderophore genes amongst multiple pathogenic bacterial strains makes siderophores attractive targets for immunizations 
  • Siderophore-based immunization may be applicable to E. coli and Klebsiella in addition to Salmonella
  • Potential increase in beneficial microbiota after immunization
  • Production of antibodies for passive immunization, which may be of therapeutic value to conditions such as irritable bowel syndrome