This technology comprises a class of durable anti-fog coatings made up of molecularly blended layers of complementary hydrophilic polymers. Thin films of these complementary polymers are alternately deposited in a layer-by-layer protocol compatible with dip, spin, or spray coating processes. The complementary polymers undergo molecular blending at layer interfaces, producing a multilayered anti-fog coating. The water-based assembly process is compatible with a wide range of substrate materials and will conform to many geometries, including parts with complex topologies. Anti-fog coatings resulting from this process exhibit good surface hardness and abrasion resistance, which can be further enhanced by inducing covalent cross-linking between layers and at the substrate-coating interface.